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Den smertestillende effekten av slike tabletter hos de fleste pasienter finnes i smertsyndromet av små og mellomstore alvor - dette refererer også til muskelsvikt og ledd. Med alvorlig ømhet er slike piller mindre effektive og noe dårligere i grad av analgesi til narkotiske analgetika.Etter å ha dominert markedet for smertestillende medisiner
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